PRXS571
PRXS571 is a potent modulator of the neuronal integrated stress response (ISR) and can be used in neural-related research[1].
Product Specifications
CAS Number
2396759-31-0
UNSPSC
12352005
Target
Eukaryotic Initiation Factor (eIF)
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/prxs571.html
Solubility
10 mM in DMSO
Smiles
FC(C=C1OC[C@H](O)CN(CC2)CCN2NC(C3=NC4=C(C=C(C=C4)Cl)C=C3)=O)=C(C=C1)Cl
Molecular Formula
C23H23Cl2FN4O3
Molecular Weight
493.36
References & Citations
[1]Marlin E, et al. Pharmacological inhibition of the integrated stress response accelerates disease progression in an amyotrophic lateral sclerosis mouse model. Br J Pharmacol. 2024 Feb;181 (3) :495-508.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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