Methylprednisolone acetate

Methylprednisolone acetate, a prednisolone derivative, is a corticosteroid hormone. Methylprednisolone acetate can relieve pain and swelling that occurs with arthritis and other joint disorders in vivo[1][2].

Product Specifications

CAS Number

[53-36-1]

UNSPSC

12352211

Hazard Statement

H361

Target

Glucocorticoid Receptor

Type

Reference compound

Related Pathways

Immunology/Inflammation; Vitamin D Related/Nuclear Receptor

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/methylprednisolone-acetate.html

Purity

95.06

Solubility

DMSO : ≥ 100 mg/mL

Smiles

C[C@@]12[C@](C(COC(C)=O)=O)(O)CC[C@@]1([H])[C@]3([H])C[C@H](C)C4=CC(C=C[C@]4(C)[C@@]3([H])[C@@H](O)C2)=O

Molecular Formula

C24H32O6

Molecular Weight

416.51

Precautions

H361

References & Citations

[1]Ha Thi -Ngan Le, et al. A mouse model of osteonecrotic femoral head induced by methylprednisolone and liposaccharide. Biomedical Research and Therapy volume 3, Article number: 12 (2016) |[2]Luis M Franco, et al. Immune regulation by glucocorticoids can be linked to cell type-dependent transcriptional responses. J Exp Med. 2019 Feb 4;216 (2) :384-406.