Scutellarein

Scutellarein is a natural flavonoid compound with anti-inflammatory effects.

Product Specifications

CAS Number

[529-53-3]

Product Name Alternative

6-Hydroxyapigenin; 4',5,6,7-Tetrahydroxyflavone

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Autophagy; SARS-CoV; Src

Type

Natural Products

Related Pathways

Anti-infection; Autophagy; Protein Tyrosine Kinase/RTK

Applications

COVID-19-anti-virus

Field of Research

Cancer; Metabolic Disease; Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Scutellarein.html

Purity

99.39

Solubility

DMSO : ≥ 30 mg/mL

Smiles

O=C1C=C(C2=CC=C(O)C=C2)OC3=CC(O)=C(O)C(O)=C13

Molecular Formula

C15H10O6

Molecular Weight

286.24

Precautions

H302, H315, H319, H335

References & Citations

[1]Sung NY, et al. Scutellarein Reduces Inflammatory Responses by Inhibiting Src Kinase Activity. Korean J Physiol Pharmacol. 2015 Sep;19 (5) :441-9.|[2]Lin Y, et al. Novel anti-obesity effect of scutellarein and potential underlying mechanism of actions. Biomed Pharmacother. 2019 Sep;117:109042.|[3]Shi X, et al. Scutellarein inhibits cancer cell metastasis in vitro and attenuates the development of fibrosarcoma in vivo. Int J Mol Med. 2015 Jan;35 (1) :31-8. |[4]Qian LH, et al. Synthesis and bio-activity evaluation of scutellarein as a potent agent for the therapy of ischemic cerebrovascular disease. Int J Mol Sci. 2011;12 (11) :8208-16.|[5]Tang H, et al. Neuroprotective effects of scutellarin and scutellarein on repeatedly cerebral ischemia-reperfusion in rats. Pharmacol Biochem Behav. 2014 Mar;118:51-9.