RIPK-IN-4
Product Specifications
UNSPSC Description
RIPK-IN-4 is a potent and selective RIPK2 inhibitor with excellent oral bioavailability, and has an IC50 of 3 nM[1].
Target Antigen
RIP kinase
Type
Reference compound
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ripk-in-4.html
Purity
99.71
Solubility
DMSO : 31.25 mg/mL (ultrasonic)
Smiles
O=S(C1=CN2C(C3=CC(N)=NC(F)=C3)=CN=C2C=C1OCC)(C(C)(C)C)=O
Molecular Weight
392.45
References & Citations
[1]He X, et al. Identification of Potent and Selective RIPK2 Inhibitors for the Treatment of Inflammatory Diseases. ACS Med Chem Lett. 2017 Sep 27;8(10):1048-1053.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-107978/RIPK-IN-4-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-107978/RIPK-IN-4-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2141969-56-2
Available Sizes
Curated Selection
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