Sitamaquine (hydrochloride)
Sitamaquine (WR6026) hydrochloride, an orally active 8-aminoquinoline analog, is an antileishmanial agent. Sitamaquine hydrochloride inhibits mitochondrial complex II (succinate dehydrogenase) . Sitamaquine hydrochloride is a lipophilic weak base that rapidly accumulates in acidic compartments of Leishmania spp., mainly in acidocalcisomes[1][2].
Product Specifications
CAS Number
5330-29-0
Product Name Alternative
WR 6026 (hydrochloride)
UNSPSC
12352005
Hazard Statement
H301-H317-H318
Target
Mitochondrial Metabolism; Parasite
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/sitamaquine-hydrochloride.html
Smiles
COC1=CC2=C(C)C=CN=C2C(NCCCCCCN(CC)CC)=C1.Cl.Cl
Molecular Formula
C21H35Cl2N3O
Molecular Weight
416.43
Precautions
P261-P264-P270-P272-P280-P302+P352-P305+P351+P338-P330-P362+P364-P405-P501
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Insulin-Like Growth Factor I, Recombinant, Human, aa49-118, His-Tag (IGF1)
Insulin-Like Growth Factor I, Recombinant, Human, aa49-118, His-Tag (IGF1)
Insulin-Like Growth Factor I, Recombinant, Human, aa49-118, His-Tag (IGF1)