Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-Hu CD85k APC

CD85k is a type I transmembrane glycoprotein of ILT/LIR family, and contains three ITIM motives, which recruit protein tyrosine phosphatases SHP-1 and SHP-2, resulting in supression of signal transduction. It is expressed by monocytes, macrophages, and dendritic cells. Antigen presenting cells expressing CD85k and CD85d appear to be crucial to the generation of CD8+ suppressor T cells and CD4+ regulatory T cells.

Product Specifications

Certification

RUO

Reactivity

Human

Immunogen

Human CD85k

Target Antigen

CD85k

Clone

ZM4.1

Applications

FC (QC tested)

Format

APC

Buffer

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

References & Citations

*Waschbisch A, Sanderson N, Krumbholz M, Vlad G, Theil D, Schwab S, Mäurer M, Derfuss T: Interferon beta and vitamin D synergize to induce immunoregulatory receptors on peripheral blood monocytes of multiple sclerosis patients. PLoS One 2014 Dec 31;9 (12) :e115488. , URL: https://pubmed.ncbi.nlm.nih.gov/25551576/, *Michalski J, Deinzer A, Stich L, Zinser E, Steinkasserer A, Knippertz I: Quercetin induces an immunoregulatory phenotype in maturing human dendritic cells. Immunobiology 2020 Jul;225 (4) :151929. , URL: https://pubmed.ncbi.nlm.nih.gov/32115260/, *Littringer K, Moresi C, Rakebrandt N, Zhou X, Schorer M, Dolowschiak T, Kirchner F, Rost F, Keller CW, McHugh D, Leibund G, Landmann S, Robinson MD, Joller N: Common features of regulatory T cell specialization during Th1 responses. Front Immunol. 2018 Jun 13;9:1344. , URL: https://pubmed.ncbi.nlm.nih.gov/29951069/, *Inui M, Sugahara-Tobinai A, Fujii H, Itoh-Nakadai A, Fukuyama H, Kurosaki T, Ishii T, Harigae H, Takai T: Tolerogenic immunoreceptor ILT3/LILRB4 paradoxically marks pathogenic auto-antibody-producing plasmablasts and plasma cells in non-treated SLE . Int Immunol. 2016 Dec;28 (12) :597-604. , URL: https://pubmed.ncbi.nlm.nih.gov/27742834/, *Chen HM, van der Touw W, Wang YS, Kang K, Mai S, Zhang J, Alsina-Beauchamp D, Duty JA, Mungamuri SK, Zhang B, Moran T, Flavell R, Aaronson S, Hu HM, Arase H, Ramanathan S, Flores R, Pan PY, Chen SH: Blocking immunoinhibitory receptor LILRB2 reprograms tumor-associated myeloid cells and promotes antitumor immunity. J Clin Invest. 2018 Dec 3;128 (12) :5647-5662. , URL: https://pubmed.ncbi.nlm.nih.gov/30352428/

Storage Conditions

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Specificity

The mouse monoclonal antibody ZM4.1 recognizes an extracellular epitope of human CD85k, a transmembrane glycoprotein expressed by monocytes, macrophages, and dendritic cells.

Applications Notes

6

Isotype

Mouse IgG1 kappa

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

U2AF2/U2AF65 Rabbit pAb
A1936-01 20 µL

U2AF2/U2AF65 Rabbit pAb

Sign In for Pricing
View Details
U2AF2/U2AF65 Rabbit pAb
A1936-02 100 μL

U2AF2/U2AF65 Rabbit pAb

Sign In for Pricing
View Details
U2AF2/U2AF65 Rabbit pAb
A1936-03 500 μL

U2AF2/U2AF65 Rabbit pAb

Sign In for Pricing
View Details
U2AF2/U2AF65 Rabbit pAb
A1936-04 1000 μL

U2AF2/U2AF65 Rabbit pAb

Sign In for Pricing
View Details
Rtn3-set siRNA/shRNA/RNAi Lentivector (Mouse)
42867094 4x 500 ng

Rtn3-set siRNA/shRNA/RNAi Lentivector (Mouse)

Sign In for Pricing
View Details
EV3150 Maxi Power Supply, 4 Outputs, 1200Volts, 500 mAmps, 300 watts - 230V
EV3150 1 Unit

EV3150 Maxi Power Supply, 4 Outputs, 1200Volts, 500 mAmps, 300 watts - 230V

Sign In for Pricing
View Details