AUPF02

AUPF02, a 5-arylurea uracil derivative, is a potent anti-breast cancer agent, with an IC50 of 23.4 µM for MCF-7 cells[1].

Product Specifications

CAS Number

[904803-58-3]

UNSPSC

12352005

Target

Amino Acid Derivatives

Type

Reference compound

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/aupf02.html

Smiles

CC1=CC=C(NC(NC2=C(F)C(F)=C(F)C(F)=C2F)=O)C=C1

Molecular Formula

C14H9F5N2O

Molecular Weight

316.23

References & Citations

[1]Sroor FM, et, al. Novel 5-Fluorouracil analogues versus perfluorophenyl ureas as potent anti-breast cancer agents: Design, robust synthesis, in vitro, molecular docking, pharmacokinetics ADMET analysis and dynamic simulations. Bioorg Chem. 2024 Dec:153:107944.