AUPF02
AUPF02, a 5-arylurea uracil derivative, is a potent anti-breast cancer agent, with an IC50 of 23.4 µM for MCF-7 cells[1].
Product Specifications
CAS Number
[904803-58-3]
UNSPSC
12352005
Target
Amino Acid Derivatives
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/aupf02.html
Smiles
CC1=CC=C(NC(NC2=C(F)C(F)=C(F)C(F)=C2F)=O)C=C1
Molecular Formula
C14H9F5N2O
Molecular Weight
316.23
References & Citations
[1]Sroor FM, et, al. Novel 5-Fluorouracil analogues versus perfluorophenyl ureas as potent anti-breast cancer agents: Design, robust synthesis, in vitro, molecular docking, pharmacokinetics ADMET analysis and dynamic simulations. Bioorg Chem. 2024 Dec:153:107944.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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