PI4KIIIbeta-IN-9

PI4KIIIbeta-IN-9 is a potent PI4KIIIβ inhibitor with an IC50 of 7 nM. PI4KIIIbeta-IN-9 also inhibits PI3Kδ and PI3Kγ with IC50s of 152 nM and 1046 nM, respectively.

Product Specifications

CAS Number

[1429624-84-9]

UNSPSC

12352005

Target

PI3K; PI4K

Type

Reference compound

Related Pathways

PI3K/Akt/mTOR

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/PI4KIIIbeta-IN-9.html

Purity

99.18

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC(N=C1NC(C2CCCC2)=O)=C(S1)C3=CC=C(C(S(=O)(NC4=CC=C(O)C=C4)=O)=C3)OC

Molecular Formula

C23H25N3O5S2

Molecular Weight

487.59

References & Citations

[1]Rutaganira FU, et al. Design and Structural Characterization of Potent and Selective Inhibitors of Phosphatidylinositol 4 Kinase IIIβ. J Med Chem. 2016 Mar 10;59 (5) :1830-9.