Cholesterol 5β,6β-epoxide

<strong>Cholesterol 5β,6β-epoxide</strong>_x000D_ <strong>Catalog number:</strong> B2018119_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 5 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 402.65_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> N/A_x000D_ <strong>Keywords:</strong> 5β,6β-Epoxycholestan-3β-ol_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Lordan S, O'Brien NM, Mackrill JJ. The role of calcium in apoptosis induced by 7beta-hydroxycholesterol and cholesterol-5beta,6beta-epoxide J Biochem Mol Toxicol. 2009 Sep-Oct;23(5):324-32._x000D_ 2: Kloudova-Spalenkova A, Ueng YF, Wei S, Kopeckova K, Peter Guengerich F, Soucek P. Plasma oxysterol levels in luminal subtype breast cancer patients are associated with clinical data J Steroid Biochem Mol Biol. 2020 Mar;197:105566._x000D_ 3: Kai T, Hirayama S, Soda S, Fuwa F, Nakagawa S, Ueno T, Hori A, Miida T. Higher concentration of 25-hydroxycholesterol in treatment-naïve patients with type 2 diabetes compared to healthy individuals J Clin Lipidol. 2023 May-Jun;17(3):384-391._x000D_ 4: Ryan L, O'Callaghan YC, O'Brien NM. The role of the mitochondria in apoptosis induced by 7beta-hydroxycholesterol and cholesterol-5beta,6beta-epoxide Br J Nutr. 2005 Oct;94(4):519-25._x000D_ 5: Lemaire-Ewing S, Prunet C, Montange T, Vejux A, Berthier A, Bessède G, Corcos L, Gambert P, Néel D, Lizard G. Comparison of the cytotoxic, pro-oxidant and pro-inflammatory characteristics of different oxysterols Cell Biol Toxicol. 2005 Mar;21(2):97-114._x000D_ 6: Lordan S, Mackrill JJ, O'Brien NM. Involvement of Fas signalling in 7beta-hydroxycholesterol-and cholesterol-5beta,6beta-epoxide-induced apoptosis Int J Toxicol. 2008;27(3):279-85._x000D_ 7: Ryan L, O'Callaghan YC, O'Brien NM. Involvement of calcium in 7beta -hydroxycholesterol and cholesterol-5beta,6beta -epoxide-induced apoptosis Int J Toxicol. 2006 Jan-Feb;25(1):35-9._x000D_ 8: Ferderbar S, Pereira EC, Apolinário E, Bertolami MC, Faludi A, Monte O, Calliari LE, Sales JE, Gagliardi AR, Xavier HT, Abdalla DS. Cholesterol oxides as biomarkers of oxidative stress in type 1 and type 2 diabetes mellitus Diabetes Metab Res Rev. 2007 Jan;23(1):35-42._x000D_ 9: Lordan S, O'Callaghan YC, O'Brien NM. Death-signaling pathways in human myeloid cells by oxLDL and its cytotoxic components 7beta-hydroxycholesterol and cholesterol-5beta,6beta-epoxide J Biochem Mol Toxicol. 2007;21(6):362-72._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/17226048">10: Vejux A, Kahn E, Ménétrier F, Montange T, Lherminier J, Riedinger JM, Lizard G. Cytotoxic oxysterols induce caspase-independent myelin figure formation and caspase-dependent polar lipid accumulation Histochem Cell Biol. 2007 Jun;127(6):609-24. </a>_x000D_ _x000D_ <strong>Products Related to Cholesterol 5β,6β-epoxide can be found at</strong> <a href="https://moleculardepot.com/product-category/Chemicals /"> Chemicals </a>