Picolinamide (Standard)
Picolinamide (Standard) is the analytical standard of Picolinamide. This product is intended for research and analytical applications. Picolinamide (2-Picolinamide) is an inhibitor of Poly (ADP-ribose) synthetase of nuclei from rat pancreatic islet cells[1][3].
Product Specifications
CAS Number
1452-77-3
Product Name Alternative
2-Picolinamide (Standard)
UNSPSC
12352005
Target
PARP; Reference Standards
Type
Reference Standards
Related Pathways
Cell Cycle/DNA Damage; Epigenetics; Others
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/picolinamide-standard.html
Smiles
O=C(C1=NC=CC=C1)N
Molecular Formula
C6H6N2O
Molecular Weight
122.12
References & Citations
[1]Campbell PI, et al. Specific inhibition of rat renal Na+/phosphate cotransport by picolinamide. J Pharmacol Exp Ther. 1989 Oct;251 (1) :188-92. |[2]Uchigata Y, et al. Protection by superoxide dismutase, catalase, and poly (ADP-ribose) synthetase inhibitors against alloxan- and streptozotocin-induced islet DNA strand breaks and against the inhibition of proinsulin synthesis. J Biol Chem. 1982 Jun 10;257 (11) :6084-8. |[3]Yamamoto H, et al. Protection by picolinamide, a novel inhibitor of poly (ADP-ribose) synthetase, against both streptozotocin-induced depression of proinsulin synthesis and reduction of NAD content in pancreatic islets. Biochem Biophys Res Commun. 1980 Jul 16;95 (1) :474-81. |[4]amagami T, et al. Induction of rat pancreatic B-cell tumors by the combined administration of streptozotocin or alloxan and poly (adenosine diphosphate ribose) synthetase inhibitors. Cancer Res. 1985 Apr;45 (4) :1845-9.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
98 100 Tests
Green Fluorescent FAM-FLICA® Caspase-1 (YVAD) Assay Kit
Sign In for Pricing
View Details 
