Fenvalerate
Fenvalerate is a potent protein phosphatase 2B (calcineurin) inhibitor with an IC50 of 2-4 nM for PP2B-Aα. Fenvalerate is a pyrethroid ester insecticide and acaricide[1].
Product Specifications
CAS Number
51630-58-1
UNSPSC
12352005
Hazard Statement
H301, H315, H319, H335, H410
Target
Bacterial; Phosphatase
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/fenvalerate.html
Concentration
10mM
Purity
99.75
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(OC(C#N)C1=CC=CC(OC2=CC=CC=C2)=C1)C(C(C)C)C3=CC=C(Cl)C=C3
Molecular Formula
C25H22ClNO3
Molecular Weight
419.90
Precautions
H301, H315, H319, H335, H410
References & Citations
[1]E Enan, et al. Specific Inhibition of Calcineurin by Type II Synthetic Pyrethroid Insecticides. Biochem Pharmacol. 1992 Apr 15;43 (8) :1777-84.|[2]A R Reilein, et al. Regulation of Organelle Movement in Melanophores by Protein Kinase A (PKA), Protein Kinase C (PKC), and Protein Phosphatase 2A (PP2A) . J Cell Biol. 1998 Aug 10;142 (3) :803-13.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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