FEFEFKFK
FEFEFKFK is an octapeptide that self-assembles into fibrillar structures. FEFEFKFK is able to form gels at concentrations greater than about 7 mg/mL. The self-assembly and gelation properties of FEFEFKFK help to understand the mechanism of amyloid fibril formation in protein misfolding diseases such as Alzheimer's disease and Parkinson's disease[1].
Product Specifications
CAS Number
883746-83-6
UNSPSC
12352209
Target
Amyloid-β
Type
Peptides
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/fefefkfk.html
Smiles
O=C(N[C@@H](CCC(O)=O)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CCCCN)C(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](CCCCN)C(O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC4=CC=CC=C4)N
Molecular Formula
C58H76N10O13
Molecular Weight
1121.28
References & Citations
[1]Mohammed A, et al. 3D Networks from Self‐Assembling Ionic‐Complementary Octa‐Peptides. Macromolecular Symposia. Weinheim: WILEY‐VCH Verlag, 2007, 251 (1) : 88-95.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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