Glucocorticoid receptor agonist-5
Glucocorticoid receptor agonist-5 (compound 4), a glucocorticoid molecule, is a potent glucocorticoid receptor agonist. Glucocorticoid receptor agonist-5 shows anti-inflammatory and immunosuppressive activity. Glucocorticoid receptor agonist-5 is used as an ADC Cytotoxin for antibody-drug conjugate[1].
Product Specifications
CAS Number
[2913231-72-6]
UNSPSC
12352005
Target
ADC Payload; Glucocorticoid Receptor
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related; Immunology/Inflammation; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/glucocorticoid-receptor-agonist-5.html
Purity
99.95
Solubility
DMSO : ≥ 50 mg/mL
Smiles
OCC([C@]12[C@@]3([C@@]([C@@]4([H])[C@]([C@@]5(C(CC4)=CC(C=C5)=O)C)([H])[C@H](C3)O)([H])C[C@@]1([H])O[C@@H](C6=CC=C(C=C6)CC7=CC=C(C=C7)CO)O2)C)=O
Molecular Formula
C36H40O7
Molecular Weight
584.70
References & Citations
[1]Xi Li, et al. Anti-bdca2 antibody-drug conjugate and use thereof. WO2024140838A1.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Traditional Cytotoxic Agents
Available Sizes
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