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Glucocorticoid receptor agonist-5

Glucocorticoid receptor agonist-5 (compound 4), a glucocorticoid molecule, is a potent glucocorticoid receptor agonist. Glucocorticoid receptor agonist-5 shows anti-inflammatory and immunosuppressive activity. Glucocorticoid receptor agonist-5 is used as an ADC Cytotoxin for antibody-drug conjugate[1].

Product Specifications

CAS Number

[2913231-72-6]

UNSPSC

12352005

Target

ADC Payload; Glucocorticoid Receptor

Type

Reference compound

Related Pathways

Antibody-drug Conjugate/ADC Related; Immunology/Inflammation; Vitamin D Related/Nuclear Receptor

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/glucocorticoid-receptor-agonist-5.html

Purity

99.95

Solubility

DMSO : ≥ 50 mg/mL

Smiles

OCC([C@]12[C@@]3([C@@]([C@@]4([H])[C@]([C@@]5(C(CC4)=CC(C=C5)=O)C)([H])[C@H](C3)O)([H])C[C@@]1([H])O[C@@H](C6=CC=C(C=C6)CC7=CC=C(C=C7)CO)O2)C)=O

Molecular Formula

C36H40O7

Molecular Weight

584.70

References & Citations

[1]Xi Li, et al. Anti-bdca2 antibody-drug conjugate and use thereof. WO2024140838A1.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Traditional Cytotoxic Agents

Available Sizes

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