PF-07258669

PF-07258669 is a melanocortin-4 receptor (MC4) antagonist. PF-07258669 can be used for the research of cachexia, anorexia, or anorexia nervosa[1].

Melanocortin Receptor

Reference compound

GPCR/G Protein;Neuronal Signaling

Metabolism-protein/nucleotide metabolism

Metabolic Disease; Neurological Disease

https://www.medchemexpress.com/pf-07258669.html

DMSO : 100 mg/mL (ultrasonic)

CC(N=C(N1)C(CC[C@]21CCN(C([C@H](C)C3=C(C=NC(OC)=C3)F)=O)C2)=C4)=C4C5=NC=CC=N5

462.52

[1]Christopher Ryan BUTLER, et al. Spiro compounds as melanocortin 4 receptor antagonists and uses thereof. Patent. WO2021250541A1.

Room Temperature

http://file.medchemexpress.com/batch_PDF/HY-148349/PF-07258669-DataSheet-MedChemExpress.pdf

http://file.medchemexpress.com/batch_PDF/HY-148349/PF-07258669-SDS-MedChemExpress.pdf

Phase 1

2755890-53-8