SMS121
Product Specifications
UNSPSC Description
SMS121 is a CD36 inhibitor with a KD values of about 5 µM. SMS121 reduces the uptake of lipids and inhibits cell viability in acute myeloid leukemia cells. SMS121 has antitumor activity[1].
Target Antigen
Scavenger Receptor Class B type I (SR-BI）
Type
Reference compound
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sms121.html
Solubility
DMSO : 13.33 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
O=C(O)COC1=CC=C(/C=C/C(C2=CC=C(N(C)C)C=C2)=O)C=C1OC
Molecular Weight
355.38
References & Citations
[1]Åbacka H, et al. SMS121, a new inhibitor of CD36, impairs fatty acid uptake and viability of acute myeloid leukemia[J]. Scientific Reports, 2024, 14(1): 9104.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-163541/SMS121-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-163541/SMS121-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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