SMS121
SMS121 is a CD36 inhibitor with a KD values of about 5 µM. SMS121 reduces the uptake of lipids and inhibits cell viability in acute myeloid leukemia cells. SMS121 has antitumor activity[1].
Product Specifications
UNSPSC
12352005
Target
Scavenger Receptor Class B type I (SR-BI)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sms121.html
Concentration
10mM
Purity
99.06
Solubility
DMSO : 13.33 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(O)COC1=CC=C(/C=C/C(C2=CC=C(N(C)C)C=C2)=O)C=C1OC
Molecular Formula
C20H21NO5
Molecular Weight
355.38
References & Citations
[1]Åbacka H, et al. SMS121, a new inhibitor of CD36, impairs fatty acid uptake and viability of acute myeloid leukemia[J]. Scientific Reports, 2024, 14 (1) : 9104.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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