P95/NBS1 (phospho-Ser343) rabbit pAb
Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq, Jul 2008],
Product Specifications
Background
UniProt
O60934
Swiss Prot
O60934
Reactivity
Human; Mouse
Immunogen
Synthesized phosho peptide around human p95 (Ser343)
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1 mg/ml
Dilution
WB 1:1000-2000
Molecular Weight
85kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
85kD
Fragment
IgG
Subcellular Location
Other Product Names
Nibrin (Cell cycle regulatory protein p95) (Nijmegen breakage syndrome protein 1)
Gene ID (Human)
4683
Available Sizes
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