P95/NBS1 (phospho-Ser343) rabbit pAb
Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Synonyms
Nibrin (Cell cycle regulatory protein p95) (Nijmegen breakage syndrome protein 1)
Gene ID
4683
UniProt
O60934
Cellular Locus
Host
Rabbit
Species Reactivity
Human,Mouse
Reactivity
Human; Mouse
Immunogen
Synthesized phosho peptide around human p95 (Ser343)
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB
Validated Applications
WB
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1:1000-2000
Molecular Weight
85kD
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES14286-1.pdf
Observed Molecular Weight
85 kD
Subcellular Location
Other Product Names
Nibrin (Cell cycle regulatory protein p95) (Nijmegen breakage syndrome protein 1)
Gene ID (Human)
4683
SwissProt (Human)
O60934
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
