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Anti-Mouse IL-27 p28 Antibody (MM27.7B1)

Selected Variant

HY-P990215-01

Size: 1 mg

Anti-Mouse IL-27 p28 Antibody (MM27.7B1) is a mouse-derived anti-mouse IL-27 p28 IgG2a, κ type antibody inhibitor. Anti-Mouse IL-27 p28 Antibody (MM27.7B1) can neutralize IL-27. Anti-Mouse IL-27 p28 Antibody (MM27.7B1) delays CD8+ T cell reconstitution mediated by IL-27 after murine anti-thymocyte globulin (mATG) treatment in BALB/c heart allografts mice models[1][2][3].

Product Specifications

CAS Number

9007-83-4

UNSPSC

12352203

Target

Interleukin Related

Type

Inhibitory Antibodies

Related Pathways

Immunology/Inflammation

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/anti-mouse-il-27-p28-antibody-mm27-7b1.html

Purity

95.00

Solubility

10 mM in DMSO

Smiles

[Anti-MouseIL-27p28Antibody(MM27.7B1)]

Molecular Weight

(150 kDa)

References & Citations

[1]Ayasoufi K, et al. Interleukin-27 promotes CD8+ T cell reconstitution following antibody-mediated lymphoablation. JCI Insight. 2019 Apr 4;4 (7) :e125489.|[2]Martin E, et al. Role of IL-27 in Epstein-Barr virus infection revealed by IL-27RA deficiency. Nature. 2024 Apr;628 (8008) :620-629.|[3]Zhu H, Lou C, Liu P. Interleukin-27 ameliorates coxsackievirus-B3-induced viral myocarditis by inhibiting Th17 cells. Virol J. 2015 Nov 14;12:189. doi: 10.1186/s12985-015-0418-xIF: 3.8 Q2 . Retraction in: Virol J. 2025 Jun 18;22 (1) :196.

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4°C for 2 years, do not freeze

Scientific Category

Inhibitory Antibodies

Clinical Information

No Development Reported

Available Sizes

Price

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