GSK2983559 (free acid)
Selected Variant
HY-112038-01
Size: 5 mg
GSK2983559 free acid (compound 3) is an orally active and potent receptor interacting protein 2 (RIP2) kinase inhibitor. GSK2983559 free acid can block many proinflammatory cytokine responses in vivo and in human inflammatory bowel disease explant samples[1].
Product Specifications
CAS Number
1579965-12-0
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
RIP kinase
Type
Reference compound
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/gsk2983559-free-acid.html
Purity
99.90
Solubility
DMSO : 5 mg/mL (ultrasonic; warming; heat to 80°C)
Smiles
CC(C)(C)S(C(C(OCCOP(O)(O)=O)=CC1=NC=N2)=CC1=C2NC3=CC(N=CS4)=C4C=C3)(=O)=O
Molecular Formula
C21H23N4O7PS2
Molecular Weight
538.53
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
RIPK2
Available Sizes
Price
Frequently Asked Questions
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