TAK1-TAB1 (1-303), (437-end), Active, GST-tagged Human

<strong>TAK1-TAB1 (1-303), (437-end), Active, GST-tagged Human</strong>_x000D_ <strong>Catalog number:</strong> B2019694_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 5 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> ~74 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> −70°C_x000D_ <strong>Keywords:</strong> MAP3K7, MGC57664, TAK1: MAP3K7_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Yuan L, Li S, Chen Q, Xia T, Luo D, Li L, Liu S, Guo S, Liu L, Du C, Jia G, Li X, Lu Z, Yang Z, Liu H, Mai H, Tang L. EBV infection-induced GPX4 promotes chemoresistance and tumor progression in nasopharyngeal carcinoma Cell Death Differ. 2022 Aug;29(8):1513-1527._x000D_ 2: Peng C, Cheng Y, Ma M, Chen Q, Duan Y, Liu S, Cheng H, Yang H, Huang J, Bu W, Shi C, Wu X, Chen J, Zheng R, Liu Z, Ji Z, Wang J, Huang X, Wang P, Sha W, Ge B, Wang L. Mycobacterium tuberculosis suppresses host antimicrobial peptides by dehydrogenating L-alanine Nat Commun. 2024 May 17;15(1):4216._x000D_ 3: Sakurai H, Nishi A, Sato N, Mizukami J, Miyoshi H, Sugita T. TAK1-TAB1 fusion protein: a novel constitutively active mitogen-activated protein kinase kinase kinase that stimulates AP-1 and NF-kappaB signaling pathways Biochem Biophys Res Commun. 2002 Oct 11;297(5):1277-81._x000D_ 4: Bao SY, Sun QX, Yao CL. The interaction of TAK1 and TAB1 enhances LPS-induced cytokine release via modulating NF-κB activation (Larimichthys crocea) Fish Shellfish Immunol. 2018 Mar;74:450-458._x000D_ 5: Zhu J, Li Q, He JT, Liu GY. Expression of TAK1/TAB1 expression in non-small cell lung carcinoma and adjacent normal tissues and their clinical significance Int J Clin Exp Pathol. 2015 Dec 1;8(12):15801-7. eCollection 2015._x000D_ 6: Liu Q, Busby JC, Molkentin JD. Interaction between TAK1-TAB1-TAB2 and RCAN1-calcineurin defines a signalling nodal control point Nat Cell Biol. 2009 Feb;11(2):154-61._x000D_ 7: Moreno-García ME, Sommer K, Rincon-Arano H, Brault M, Ninomiya-Tsuji J, Matesic LE, Rawlings DJ. Kinase-independent feedback of the TAK1/TAB1 complex on BCL10 turnover and NF-κB activation Mol Cell Biol. 2013 Mar;33(6):1149-63._x000D_ 8: Shim JH, Xiao C, Paschal AE, Bailey ST, Rao P, Hayden MS, Lee KY, Bussey C, Steckel M, Tanaka N, Yamada G, Akira S, Matsumoto K, Ghosh S. TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo Genes Dev. 2005 Nov 15;19(22):2668-81._x000D_ 9: Yu-Wei D, Li ZS, Xiong SM, Huang G, Luo YF, Huo TY, Zhou MH, Zheng YW. Paclitaxel induces apoptosis through the TAK1-JNK activation pathway FEBS Open Bio. 2020 Aug;10(8):1655-1667._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/35760111">10: Song Y, Xu C, Wu J, Shu J, Sheng H, Shen Y. Palmatine alleviates LPS-induced acute lung injury via interfering the interaction of TAK1 and TAB1 Biochem Pharmacol. 2022 Aug;202:115120. </a>_x000D_ _x000D_ <strong>Products Related to TAK1-TAB1 (1-303), (437-end), Active, GST-tagged Human can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>