E3 ligase Ligand 26

E3 ligase Ligand 26 (part of Compd 10) is a ligand for E3 ligase, used for the synthesis of PROTAC SOS1 degrader (HY-161636) [1].

Product Specifications

CAS Number

[2911613-35-7]

UNSPSC

12352005

Target

Ligands for E3 Ligase

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/e3-ligase-ligand-26.html

Smiles

O=C(NC1=O)CCN1C2=C(C)C=CC(C(OC3=C(F)C(F)=C(F)C(F)=C3F)=O)=C2

Molecular Formula

C18H11F5N2O4

Molecular Weight

414.28

References & Citations

[1]Zhengqing Ye, et al. Sos1 protein degradation agent and use thereof. Patent. WO2024083257A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Cereblon

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

NBP2-60609 1 Kit

Human VTA1 ELISA Kit (Colorimetric)

Ask

View Details

MBS9942304-01 48 Well

Sheep Bifunctional Purine Biosynthesis Protein PURH [Includes:Phosphoribosylaminoimidazolecarboxamide Formyltransferase] (ATIC) ELISA Kit

Ask

View Details

MBS9942304-02 96 Well

Sheep Bifunctional Purine Biosynthesis Protein PURH [Includes:Phosphoribosylaminoimidazolecarboxamide Formyltransferase] (ATIC) ELISA Kit

Ask

View Details

MBS9942304-03 5x 96 Well

Sheep Bifunctional Purine Biosynthesis Protein PURH [Includes:Phosphoribosylaminoimidazolecarboxamide Formyltransferase] (ATIC) ELISA Kit

Ask

View Details

MBS9942304-04 10x 96 Well

Sheep Bifunctional Purine Biosynthesis Protein PURH [Includes:Phosphoribosylaminoimidazolecarboxamide Formyltransferase] (ATIC) ELISA Kit

Ask

View Details

HK301243 200 Reactions

MIR5689 Human qPCR Template Standard (MI0019294)

Ask

View Details