E3 ligase Ligand 26
E3 ligase Ligand 26 (part of Compd 10) is a ligand for E3 ligase, used for the synthesis of PROTAC SOS1 degrader (HY-161636) [1].
Product Specifications
CAS Number
[2911613-35-7]
UNSPSC
12352005
Target
Ligands for E3 Ligase
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/e3-ligase-ligand-26.html
Smiles
O=C(NC1=O)CCN1C2=C(C)C=CC(C(OC3=C(F)C(F)=C(F)C(F)=C3F)=O)=C2
Molecular Formula
C18H11F5N2O4
Molecular Weight
414.28
References & Citations
[1]Zhengqing Ye, et al. Sos1 protein degradation agent and use thereof. Patent. WO2024083257A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GTR15190593 1 Vial
Lentiviral mouse Zfp1 shRNA (UAS) - Lentiviral mouse Zfp1 shRNA (UAS, GFP) (100)
Ask
View Details 
RC215516L4 10 µg
Inosine triphosphate pyrophosphatase (ITPA) (NM_181493) Human Tagged Lenti ORF Clone
Ask
View Details 