E3 ligase Ligand 26
E3 ligase Ligand 26 (part of Compd 10) is a ligand for E3 ligase, used for the synthesis of PROTAC SOS1 degrader (HY-161636) [1].
Product Specifications
CAS Number
[2911613-35-7]
UNSPSC
12352005
Target
Ligands for E3 Ligase
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/e3-ligase-ligand-26.html
Smiles
O=C(NC1=O)CCN1C2=C(C)C=CC(C(OC3=C(F)C(F)=C(F)C(F)=C3F)=O)=C2
Molecular Formula
C18H11F5N2O4
Molecular Weight
414.28
References & Citations
[1]Zhengqing Ye, et al. Sos1 protein degradation agent and use thereof. Patent. WO2024083257A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
Curated Selection
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