E3 ligase Ligand 26

E3 ligase Ligand 26 (part of Compd 10) is a ligand for E3 ligase, used for the synthesis of PROTAC SOS1 degrader (HY-161636) [1].

Product Specifications

CAS Number

[2911613-35-7]

UNSPSC

12352005

Target

Ligands for E3 Ligase

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/e3-ligase-ligand-26.html

Smiles

O=C(NC1=O)CCN1C2=C(C)C=CC(C(OC3=C(F)C(F)=C(F)C(F)=C3F)=O)=C2

Molecular Formula

C18H11F5N2O4

Molecular Weight

414.28

References & Citations

[1]Zhengqing Ye, et al. Sos1 protein degradation agent and use thereof. Patent. WO2024083257A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Cereblon

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