Thalidomide-pyrrolidine (hydrochloride)
Thalidomide-pyrrolidine hydrochloride (compound 18) is an E3 ligase ligand, and can be used for synthesis of PROTACs[1].
Product Specifications
CAS Number
[2616553-35-4]
UNSPSC
12352005
Target
Ligands for E3 Ligase
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/androgen-receptor-degrader-1.html
Purity
98.94
Solubility
10 mM in DMSO
Smiles
O=C1NC(C(CC1)N2C(C3=C(C2=O)C=C(CNC4)C4=C3)=O)=O.[H]Cl
Molecular Formula
C15H14ClN3O4
Molecular Weight
335.74
References & Citations
[1]Shao MW, et, al. Androgen receptor protein degraders with a tricyclic cereblon ligand. WO2021231927A1.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature, keep dry and cool
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
Available Sizes
Curated Selection
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