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Human FGF-7 / HBGF-7 / KGF Protein, premium grade

Human FGF-7 Protein, premium grade (FG7-H5213) is expressed from human 293 cells (HEK293) . It contains AA Cys 32 - Thr 194 (Accession # P21781-1) .

Product Specifications

Background

Fibroblast growth factor (FGF) 7 (is also known as Keratinocyte growth factor (KGF) ), a member of FGF family, is initially found to be secreted from mesenchymal cells to repair epithelial tissues. As a well-characterized paracrine growth factor for tissue growth and regeneration, fibroblast growth factor 7 (FGF7) is involved in a number of physiological and pathological processes, including lung disease and cancer. The stromal-derived FGFs, such as FGF7 and FGF10, control epithelial cell resident FGFR2IIIb activities, promote net tissue homeostasis, and restraint tumor cells from progression to malignancy.

Specifications

This protein carries no "tag". The protein has a calculated MW of 19.0 kDa. The protein migrates as 27 kDa±3 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.

Accession Number

P21781-1

Expression Region

Cys 32 - Thr 194

Host

HEK293

Target

FGF-7

Conjugation

Unconjugated

Tag

Native

Source

Human

Stability

● -20°C to -70°C for 24 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

0.01 EU per μg

Purity

95%

Bioactivity

Immobilized Human FGF-7 Protein, premium grade (Cat. No. FG7-H5213) at 5 μg/mL (100 μL/well) can bind Human FGF R2 (IIIb), Fc Tag (Cat. No. FGB-H5256) with a linear range of 2-78 ng/mL (QC tested).

Format

Powder

Buffer

PBS, pH7.4

Additives

Trehalose

Molecular Weight

19.0 kDa

Shipping Conditions

RT

Storage Conditions

-20°C

Package Size

250ug*4

Product Datasheet

Https://www.acrobiosystems.com/static/main/products/pdf/ds/FG7-H5213.pdf

Species

Human

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