CYM50358 (hydrochloride)

CYM50358 hydrochloride (compound 4v) is a potent, selective sphingosine-1-phosphate 4 (S1P4) receptor antagonist. CYM50358 hydrochloride can be used in the study of influenza infection[1].

Product Specifications

CAS Number

[1781750-72-8]

UNSPSC

12352005

Hazard Statement

H301-H311-H331

Target

LPL Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/cym50358-hydrochloride.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=CC=C(O1)C2=C(C=CC(Cl)=C2)Cl)NC3=C(C=C(C=C3C)CN)C.Cl

Molecular Formula

C20H19Cl3N2O2

Molecular Weight

425.74

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P403+P233-P405-P501

References & Citations

[1]Guerrero M, et al. Discovery, design and synthesis of the first reported potent and selective sphingosine-1-phosphate 4 (S1P4) receptor antagonists. Bioorg Med Chem Lett. 2011 Jun 15;21 (12) :3632-6.