Cdc7-IN-21

Cdc7-IN-21 (compound 10c) is a potent and selective Cdc7 inhibitor with an IC50 of 0.07 nM. Cdc7-IN-21 can be used to study cancer[1].

Product Specifications

CAS Number

[1330781-04-8]

UNSPSC

12352005

Target

CDK

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cdc7-in-21.html

Solubility

10 mM in DMSO

Smiles

O=C1N=C(CN2CCCC2)NC3=C1SC(C4=CNN=C4C)=C3

Molecular Formula

C15H17N5OS

Molecular Weight

315.39

References & Citations

[1]Kurasawa O, et al. 2-Aminomethylthieno [3, 2-d] pyrimidin-4 (3H) -ones bearing 3-methylpyrazole hinge binding moiety: Highly potent, selective, and time-dependent inhibitors of Cdc7 kinase[J]. Bioorganic & Medicinal Chemistry, 2017, 25 (14) : 3658-3670.