Cdc7-IN-21
Cdc7-IN-21 (compound 10c) is a potent and selective Cdc7 inhibitor with an IC50 of 0.07 nM. Cdc7-IN-21 can be used to study cancer[1].
Product Specifications
CAS Number
[1330781-04-8]
UNSPSC
12352005
Target
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cdc7-in-21.html
Solubility
10 mM in DMSO
Smiles
O=C1N=C(CN2CCCC2)NC3=C1SC(C4=CNN=C4C)=C3
Molecular Formula
C15H17N5OS
Molecular Weight
315.39
References & Citations
[1]Kurasawa O, et al. 2-Aminomethylthieno [3, 2-d] pyrimidin-4 (3H) -ones bearing 3-methylpyrazole hinge binding moiety: Highly potent, selective, and time-dependent inhibitors of Cdc7 kinase[J]. Bioorganic & Medicinal Chemistry, 2017, 25 (14) : 3658-3670.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6384954-01 0.1 mL
MARCH10 (Probable E3 Ubiquitin-protein Ligase MARCH10, Membrane-associated RING Finger Protein 10, Membrane-associated RING-CH Protein X, MARCH-X, RING Finger Protein 190, RNF190, FLJ35757) (HRP)
Ask
View Details 
MBS6384954-02 5x 0.1 mL
MARCH10 (Probable E3 Ubiquitin-protein Ligase MARCH10, Membrane-associated RING Finger Protein 10, Membrane-associated RING-CH Protein X, MARCH-X, RING Finger Protein 190, RNF190, FLJ35757) (HRP)
Ask
View Details 
221496-01 50 µL
CD31 (Platelet Endothelial Cell Adhesion Molecule, PECAM-1, EndoCAM, GPIIA', PECA1, CD31, PECAM1) discontinued
Ask
View Details 221496-02 100 µL
CD31 (Platelet Endothelial Cell Adhesion Molecule, PECAM-1, EndoCAM, GPIIA', PECA1, CD31, PECAM1) discontinued
Ask
View Details