TL13-68
TL13-68 is a biotin-tagged version of SM1-71, and it can be used to research the mechanism of SM1-71[1].
Product Specifications
UNSPSC
12352005
Target
FGFR; LIM Kinase (LIMK) ; MAP3K; Ribosomal S6 Kinase (RSK) ; Src
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; MAPK/ERK Pathway; Protein Tyrosine Kinase/RTK
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/tl13-68.html
Purity
98.88
Solubility
DMSO : 150 mg/mL (ultrasonic)
Smiles
O=C1N[C@@H]2[C@H](CCCCC(NCCOCCOCCOCCN3CCN(CC3)C(C=C4)=CC=C4NC(N=C5NC6=C(C=CC=C6)NC(C=C)=O)=NC=C5Cl)=O)SC[C@@H]2N1
Molecular Formula
C41H55ClN10O6S
Molecular Weight
851.46
References & Citations
[1]Du G, et, al. Structure-Based Design of a Potent and Selective Covalent Inhibitor for SRC Kinase That Targets a P-Loop Cysteine. J Med Chem. 2020 Feb 27; 63 (4) : 1624-1641.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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