DMG-PEG

DMG-PEG is used for the preparation of liposome for siRNA delivery with improved transfection efficiency in vitro. DMG-PEG is also used for the lipid nanoparticle for an oral plasmid DNA delivery approach in vivo through a facile surface modification to improve the mucus permeability and delivery efficiency of the nanoparticles[1].

Product Specifications

CAS Number

[1397695-86-1]

UNSPSC

12352200

Hazard Statement

H315-H319

Target

Liposome

Type

Biochemical Assay Reagents

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/dmg-peg.html

Smiles

CCCCCCCCCCCCCC(OC(COCCOC)COC(CCCCCCCCCCCCC)=O)=O.[n]

Precautions

P264-P280-P302+P352-P362+P364

References & Citations

[1]Nie T, et al. Surface Coating Approach to Overcome Mucosal Entrapment of DNA Nanoparticles for Oral Gene Delivery of Glucagon-like Peptide 1. ACS Appl Mater Interfaces. 2019 Aug 21;11 (33) :29593-29603.