Etofenamate

Etofenamate, a non-steroid anti-inflammatory agent (NSAID) and a non-selective COX inhibitor, possesses analgesic, anti-rheumatic, antipyretic and anti-inflammatory properties. Etofenamate is used in the research for osteoarthritis, arthritis and other inflammatory diseases[1][2][3].

Product Specifications

CAS Number

[30544-47-9]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

COX

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/etofenamate.html

Purity

98.26

Solubility

DMSO : ≥ 50 mg/mL|Ethanol : 120 mg/mL (ultrasonic)

Smiles

O=C(OCCOCCO)C1=CC=CC=C1NC2=CC=CC(C(F)(F)F)=C2

Molecular Formula

C18H18F3NO4

Molecular Weight

369.34

Precautions

H302, H315, H319, H335

References & Citations

[1]Bender T, Bariska J, Rojkovich B, Bálint G. Etofenamate levels in human serum and synovial fluid following iontophoresis. Arzneimittelforschung. 2001;51 (6) :489-92.|[2]Fraga A, de Almeida M, Moreira-da-Silva V et al. Intramuscular Etofenamate versus Diclofenac in the Relief of Renal Colic : A Randomised, Single-Blind, Comparative Study. Clin Drug Investig. 2003;23 (11) :701-6.|[3]Joana Marto, et al. Topical gels of etofenamate: in vitro and in vivo evaluation. Pharm Dev Technol. 2015;20 (6) :710-5.