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KIF18A-IN-12

KIF18A-IN-12 (compound 9) is a KIF18A inhibitor, with an IC50 value of 45.54 nM. KIF18A-IN-12 can be used in cancer research[1].

Product Specifications

CAS Number

[3033980-95-6]

UNSPSC

12352005

Target

Kinesin; Microtubule/Tubulin

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/kif18a-in-12.html

Smiles

CC1=CC(N2CCC(F)(CC2)F)=NC(NC(C3=C(C=C(C4=C3CCC4)NS(=O)(CCO)=O)N5CCC6(CC6)CC5)=O)=C1

Molecular Formula

C30H39F2N5O4S

Molecular Weight

603.72

References & Citations

[1]Lu biao, et al.Fused ring kif18a inhibitor compound, pharmaceutical composition, and preparation method therefor and use thereof. patent. WO2024067675A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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