Human IL-17 RA/IL-17 RC (Luc) HEK293 Reporter Cell
Human IL-17 RA/IL-17 RC (Luc) HEK293 Reporter Cell is expressed from Human HEK293.
Product Specifications
Background
Cytokine binding triggers homotypic interaction of IL17RA and IL17RC chains with TRAF3IP2 adapter, leading to TRAF6-mediated activation of NF-kappa-B and MAPkinase pathways, ultimately resulting in transcriptional activation of cytokines, chemokines, antimicrobial peptides and matrix metalloproteinases, with potential strong immune inflammation.
Host
HEK293
Origin Species
Human
Target
IL-17 RA & IL-17 RC
Tag
Luc
Applications
• Screen for neutralizing antibodies blocking the stimulation of human IL-17A or human IL-17F protein.
Format
Liquid
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
Dry ice
Storage Conditions
Frozen in liquid nitrogen
Package Size
1Vial*2
Host or Source
HEK293
Species
Human
Curated Selection
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