Anti-Mouse CD4 Antibody (GK1.5)

Anti-Mouse CD4 Antibody (GK1.5) is an anti-mouse CD4 IgG2b monoclonal antibody. Anti-Mouse CD4 Antibody (GK1.5) can significantly deplete CD4+ T cells. Anti-Mouse CD4 Antibody (GK1.5) can extend the survival rate of xenograft models. Anti-Mouse CD4 Antibody (GK1.5) can be used for research on immunology. The recommend isotype control of Anti-Mouse CD4 Antibody (GK1.5) : Rat IgG2b kappa, Isotype Control (HY-P990682) [1][2][3].

Product Specifications

CAS Number

[9007-83-4]

UNSPSC

12352203

Target

Transmembrane Glycoprotein

Type

Inhibitory Antibodies

Related Pathways

Immunology/Inflammation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/anti-mouse-cd4-antibody-gk1-5.html

Purity

99.16

Smiles

[Anti-MouseCD4Antibody(GK1.5)]

Molecular Weight

(150 kDa)

References & Citations

[1]Yi H, et al. Depleting anti-CD4 monoclonal antibody (GK1.5) treatment: influence on regulatory CD4+CD25+Foxp3+ T cells in mice. Transplantation. 2008 Apr 27;85 (8) :1167-74.|[2]Ni Q, et al. Gut microbiota dysbiosis orchestrates vitiligo-related oxidative stress through the metabolite hippuric acid. Microbiome. 2025 May 6;13 (1) :112.|[3]Fujinami N, et al. Enhancement of antitumor effect by peptide vaccine therapy in combination with anti-CD4 antibody: Study in a murine model. Biochem Biophys Rep. 2016 Feb 19;5:482-491.|[4]Simeonovic CJ, et al. Effect of GK1.5 monoclonal antibody dosage on survival of pig proislet xenografts in CD4+ T cell-depleted mice. Transplantation. 1990 May;49 (5) :849-56.