N-MeVal-Val-Dil-Dap-2- (pyridin-3-yl) ethanamine
N-MeVal-Val-Dil-Dap-2- (pyridin-3-yl) ethanamine (Compound 14) is a tubulin polymerization inhibitor that can be used as an ADC payload[1].
Product Specifications
CAS Number
1448364-29-1
UNSPSC
12352203
Target
ADC Payload; Microtubule/Tubulin
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/n-meval-val-dil-dap-2-pyridin-3-yl-ethanamine.html
Smiles
CC(C)[C@@H](C(N[C@@H](C(C)C)C(N(C)[C@@H]([C@H](CC)C)[C@H](OC)CC(N1[C@H]([C@H](OC)[C@@H](C)C(NCCC2=CN=CC=C2)=O)CCC1)=O)=O)=O)NC
Molecular Formula
C37H64N6O6
Molecular Weight
688.94
References & Citations
[1]Mendelsohn BA, et, al. Investigation of Hydrophilic Auristatin Derivatives for Use in Antibody Drug Conjugates. Bioconjug Chem. 2017 Feb 15;28 (2) :371-381.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Frequently Asked Questions
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