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N-MeVal-Val-Dil-Dap-2-(pyridin-3-yl)ethanamine

Product Specifications

UNSPSC Description

N-MeVal-Val-Dil-Dap-2-(pyridin-3-yl)ethanamine (Compound 14) is a tubulin polymerization inhibitor that can be used as an ADC payload[1].

Target Antigen

ADC Cytotoxin; Microtubule/Tubulin

Type

Reference compound

Related Pathways

Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage;Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/n-meval-val-dil-dap-2-pyridin-3-yl-ethanamine.html

Smiles

CC(C)[C@@H](C(N[C@@H](C(C)C)C(N(C)[C@@H]([C@H](CC)C)[C@H](OC)CC(N1[C@H]([C@H](OC)[C@@H](C)C(NCCC2=CN=CC=C2)=O)CCC1)=O)=O)=O)NC

Molecular Weight

688.94

References & Citations

[1]Mendelsohn BA, et, al. Investigation of Hydrophilic Auristatin Derivatives for Use in Antibody Drug Conjugates. Bioconjug Chem. 2017 Feb 15;28(2):371-381.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-164787/N-MeVal-Val-Dil-Dap-2-pyridin-3-yl-ethanamine-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-164787/

Clinical Information

No Development Reported

CAS Number

1448364-29-1

Curated Selection

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