Aminocandin
Aminocandin (HMR 3270) is water-soluble antifungal agent of the echinocandin class with excellent activity against Aspergillus and Candida spp.[1].
Product Specifications
CAS Number
227472-48-2
Product Name Alternative
HMR 3270; IP960; NXL201
UNSPSC
12352209
Target
Fungal
Type
Peptides
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/aminocandin.html
Solubility
10 mM in DMSO
Smiles
O=C([C@@H](NC([C@](NC([C@@](C[C@H]1O)([H])N(C1)C2=O)=O)([H])[C@H](O)CC(C=C3)=CC=C3O)=O)CO)N(C[C@@H]4C)[C@@](C(NCC(C[C@@H](C(N[C@@]2([H])[C@H](O)C)=O)NC(C5=CC=C(C(C=C6)=CC=C6OCCCCCCCC)C=C5)=O)NCCN)=O)([H])[C@H]4O
Molecular Formula
C56H79N9O14
Molecular Weight
1102.28
References & Citations
[1]Warn PA, et al. Activity of aminocandin (IP960; HMR3270) compared with amphotericin B, itraconazole, caspofungin and micafungin in neutropenic murine models of disseminated infection caused by itraconazole-susceptible and -resistant strains of Aspergillus fumigatus. Int J Antimicrob Agents. 2010 Feb;35 (2) :146-51.|[2]Ghannoum MA, et al. Efficacy of aminocandin in the treatment of immunocompetent mice with haematogenously disseminated fluconazole-resistant candidiasis. J Antimicrob Chemother. 2007 Mar;59 (3) :556-9.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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