Depulfavirine
Product Specifications
Product Name Alternative
Ro-0335
UNSPSC Description
RO-0335 is a novel and potent diphenylether nonnucleoside reverse transcriptase inhibitor(NNRTI). RO-0335 inhibits Wt HIV-1 with an IC50 of 1.1 nM and retained activity (IC50[1].
Target Antigen
Reverse Transcriptase
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ro-0335.html
Purity
99.48
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
ClC1=CC(OC2=C(F)C(CC(NC3=CC=C(S(=O)(N)=O)C=C3Cl)=O)=CC=C2Br)=CC(C#N)=C1
Molecular Weight
573.22
References & Citations
[1]Javanbakht H, et al. In vitro resistance development for RO-0335, a novel diphenylether nonnucleoside reverse transcriptase inhibitor. Antiviral Res. 2010;86(2):212-219.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-13053/Depulfavirine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-13053/Depulfavirine-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
867365-76-2
Available Sizes
Curated Selection
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