Adelmidrol
Adelmidrol exerts important anti-inflammatory effects that are partly dependent on PPARγ. Adelmidrol reduces NF-κB translocation, and COX-2 expression.
Product Specifications
CAS Number
[1675-66-7]
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
COX; NF-κB; PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-anti-virus
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Adelmidrol.html
Concentration
10mM
Purity
98.0
Solubility
DMSO : ≥ 100 mg/mL|H2O : ≥ 100 mg/mL
Smiles
O=C(NCCO)CCCCCCCC(NCCO)=O
Molecular Formula
C13H26N2O4
Molecular Weight
274.36
Precautions
H302, H315, H319, H335
References & Citations
[1]Cordaro M, et al. Adelmidrol, a Palmitoylethanolamide Analogue, as a New Pharmacological Treatment for the Management of Inflammatory Bowel Disease. Mol Pharmacol. 2016 Nov;90 (5) :549-561.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Isoform
COX-2; NF-κB; PPARγ
Available Sizes
Curated Selection
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