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Narnatumab

Narnatumab (IMC-RON8) is a neutralizing human monoclonal antibody that blocks RON binding to its ligand, macrophage-stimulating protein (MSP), with a Kd of 32 pM. Narnatumab can be used for the research of cancer[1].

Product Specifications

CAS Number

[1188275-92-4]

Product Name Alternative

IMC-RON8; LY3012219; Anti-MSPR/RON/CD136 Reference Antibody (narnatumab)

UNSPSC

12352203

Target

C-Met/HGFR; Tyrosinase

Type

Inhibitory Antibodies

Related Pathways

Metabolic Enzyme/Protease; Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/narnatumab.html

Purity

99.93

Solubility

H2O

Smiles

[Narnatumab]

Molecular Weight

(145.8 kDa)

References & Citations

[1]LoRusso PM, et, al. Phase 1 study of narnatumab, an anti-RON receptor monoclonal antibody, in patients with advanced solid tumors. Invest New Drugs. 2017 Aug;35 (4) :442-450.

Shipping Conditions

Dry Ice

Storage Conditions

Store at -80°C for 2 years

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-P99375/Narnatumab-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-P99375/Narnatumab-SDS-MedChemExpress.pdf

Scientific Category

Inhibitory Antibodies

Clinical Information

Phase 1

Available Sizes

Curated Selection

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