Stigmane B
Stigmane B (Compound 2) is a nuclear factor E2-related factor (Nrf2) activator. Stigmane B downregulates apoptosis and reactive oxygen species (ROS) generation, and increases antioxidant enzyme activities. Stigmane B shows neuroprotective effects[1].
Product Specifications
UNSPSC
12352211
Target
Keap1-Nrf2
Type
Natural Products
Related Pathways
NF-κB
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/stigmane-b.html
Solubility
10 mM in DMSO
Smiles
COC([C@@]1(CCC[C@]2([C@H]3[C@@]4(CC[C@]12[H])C[C@H](C(C(O)=O)=C4)CC3)C)C)=O
Molecular Formula
C21H30O4
Molecular Weight
346.46
References & Citations
[1]Song XY, et al. Terpenoids from stigma maydis (Zea mays L.) alleviate hydrogen peroxide-induced SH-SY5Y cell injury by activating Nrf2. Bioorg Chem. 2020 Sep;102:104131.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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