E3 Ligase Ligand-linker Conjugate 129
E3 Ligase Ligand-linker Conjugate 129 is an E3 ligase ligand-linker conjugate. E3 Ligase Ligand-linker Conjugate 129 can be used to synthesize DD205-291.
Product Specifications
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/e3-ligase-ligand-linker-conjugate-129.html
Smiles
O=C(N(CC1)C2=C(Cl)C=CC(C(N3CCC(CC4CCN(CC4)C(OC(C)(C)C)=O)CC3)=O)=C2)NC1=O
Molecular Formula
C27H37ClN4O5
Molecular Weight
533.06
References & Citations
[1]Zhimin Zhang, et al. Discovery of Novel PROTAC-Based HPK1 Degraders with High Potency and Selectivity for Cancer Immunotherapy. J Med Chem. 2024 Nov 14;67 (21) :18682-18698.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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