Human Integrin isoform alpha-7X2B beta 1 (ITGA7X2B&ITGB1) Heterodimer Protein, His Tag&Tag Free
Integrin alpha-7/beta-1 is the primary laminin receptor on skeletal myoblasts and adult myofibers, which is highly expressed in cardiac muscle, skeletal muscle and smooth muscle cells, and localizes to Z-disc and costamere structures. It is involved in the maintenance of the myofibers cytoarchitecture as well as for their anchorage, viability and functional integrity. Isoform Alpha-7X2B and isoform Alpha-7X1B promote myoblast migration on laminin 1 and laminin 2/4, but isoform Alpha-7X1B is less active on laminin 1 (In vitro) . ITGA7 has been shown to interact with Merosin, ITGB1, FHL2 and FHL3.
Product Specifications
Background
Specifications
Accession Number
Q13683-7 (ITGA7X2B) & P05556-1 (ITGB1)
Expression Region
Phe 34 - Trp 1038 (ITGA7X2B) & Gln 21 - Asp 728 (ITGB1)
Host
HEK293
Target
Integrin isoform alpha-7X2B beta 1
Conjugation
Unconjugated
Tag
C-10xHis | Native
Source
Human
Stability
Endotoxin
1.0 EU per μg
Purity
90%
Bioactivity
Format
Powder
Buffer
50 mM Tris, 150 mM NaCl, pH7.5
Additives
Trehalose
Molecular Weight
116.5 kDa (ITGA7X2B) & 83.7 kDa (ITGB1)
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
200ug*5
Host or Source
HEK293
Species
Human
Protein ID
Q13683-7 (ITGA7X2B) & P05556-1 (ITGB1)
Preservative
Trehalose
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