HMAO-B-IN-10
HMAO-B-IN-10 (compound 7) is an inhibitor of MAO-A/B with IC50 of 424.1 nM and 177.9 nM, respectively. hMAO-B-IN-10 exerts a certain neuroprotective effect in MPTP -induced mouse PD model.[1].
Product Specifications
UNSPSC
12352005
Target
Monoamine Oxidase
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/hmao-b-in-10.html
Smiles
O=C(N)COC1=CC=C(/C=C/C2=CC(C#N)=CN=C2)C([N+]([O-])=O)=C1
Molecular Formula
C16H12N4O4
Molecular Weight
324.29
References & Citations
[1]Knez D, et al. Development of novel aza-stilbenes as a new class of selective MAO-B inhibitors for the treatment of Parkinson's disease. Bioorg Chem. 2024 Dec;153:107877.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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