FRα-targeting peptide C7

FRα-targeting peptide C7 is a selective peptide ligand for folate receptor α (FRα) that has specific binding to FRα expressing cells and in vivo tumor targeting ability. FRα-targeting peptide C7 can be used in the research of tumor diagnosis and treatment[1].

Product Specifications

CAS Number

[2159055-74-8]

UNSPSC

12352209

Target

Antifolate

Type

Peptides

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/frα-targeting-peptide-c7.html

Smiles

O=C(N[C@@H](CC1=CNC=N1)C(N[C@@H]([C@H](O)C)C(N[C@@H](C)C(N2[C@@H](CCC2)C(NCC(N[C@@H](CC3=CNC4=CC=CC=C34)C(NCC(N[C@@H](CC5=CC=C(C=C5)O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(N[C@@H](CO)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCSC)N

Molecular Formula

C62H90N18O16S

Molecular Weight

1375.55

References & Citations

[1]Junxing Li, et al. Identification of a peptide for folate receptor alpha by phage display and its tumor targeting activity in ovary cancer xenograft[J]. Scientific reports, 2018, 8 (1) : 8426.