9-Hydroxy-α-lapachone

9-Hydroxy-α-lapachone (α-Dihydrocaryopterone) is a natural phenol, exhibits potent inhibitory effects with an IC50 of 4.64 µM on LPS-induced NO production in RAW 264.7 cells[1].

Product Specifications

CAS Number

[22333-58-0]

Product Name Alternative

α-Dihydrocaryopterone

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

NO Synthase

Type

Natural Products

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/9-hydroxy-α-lapachone.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=C2OC(C)(C)CC1)C3=C(C2=O)C(O)=CC=C3

Molecular Formula

C15H14O4

Molecular Weight

258.27

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Byeong Min Park, et al. Naphthoquinones from Catalpa ovata and their inhibitory effects on the production of nitric oxide. Arch Pharm Res. 2010 Mar;33 (3) :381-5.