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Dehydrotrametenolic acid

Dehydrotrametenolic acid is a sterol isolated from the sclerotium of Poria cocos. Dehydrotrametenolic acid induces apoptosis through caspase-3 pathway. Dehydrotrametenolic acid has anti-tumor activity, anti-inflammatory, anti-diabetic effects[1].

Product Specifications

CAS Number

[6879-05-6]

UNSPSC

12352211

Target

Apoptosis; Caspase

Type

Natural Products

Related Pathways

Apoptosis

Applications

Neuroscience-Neurodegeneration

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/dehydrotrametenolic-acid.html

Purity

99.95

Solubility

DMSO : 1 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

C[C@]12C3=CC[C@](C(C)([C@@H](O)CC4)C)([H])[C@@]4(C)C3=CC[C@@]1([C@]([C@H](C(O)=O)CCC(C(C)C)=C)([H])CC2)C

Molecular Formula

C31H48O3

Molecular Weight

468.71

References & Citations

[1]Kang HM, et al. Dehydrotrametenolic acid selectively inhibits the growth of H-ras transformed rat2 cells and induces apoptosis through caspase-3 pathway. Life Sci. 2006 Jan 2;78 (6) :607-13.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

Caspase 3

Available Sizes

Curated Selection

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