Purified Anti-Human CD180 Antibody[G28-8]
Product Specifications
Background
CD180, also known as RP105, is a 105 kD member of the toll-like receptor (TLR) family and is expressed on most B cells, monocytes/macrophages and dendritic cells. The TLR family's structural characteristics are critically involved in protein-protein signaling interactions leading to the activation of the innate immune system. Additionally, MD-1, a secretory protein, associates with CD180 (RP105) at the cell surface and this complex, in conjunction with TLR4, recognizes bacterial LPS. The human CD180 (RP105) gene maps to 5q12. The MHR73-11 antibody is able to activate B cells and to protect against irradiation- or dexamethasone-induced apoptosis.
Abbreviation
CD180
Gene ID
4064
UniProt
Q99467
Host
Mouse
Reactivity
Human
Immunogen
Recombinant Human CD180 protein
Target
LY64; RP105; CD180; Ly78
Clonality
Monoclonal
Clone
G28-8
Conjugation
Unconjugated
Applications
FCM
Field of Research
Immunology; Microbiology
Purification
>98%, Protein A/G purified
Concentration
≥ 1 mg/mL
Dilution
66
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Isotype
Mouse IgG1, κ
Available Sizes
Curated Selection
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