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HMG-CoA

HMG-CoA is a product generated by the hydration reaction of (E) -3-methylglutaconyl-CoA (MG-CoA) catalyzed by methylglutaconyl-CoA hydratase (MGCH) [1].

Product Specifications

CAS Number

1553-55-5

Product Name Alternative

3-Hydroxy-3-methylglutaryl-CoA

UNSPSC

12352204

Target

Acetyl-CoA synthetase

Type

Enzyme

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/hmg-coa.html

Solubility

10 mM in DMSO

Smiles

NC1=NC=NC2=C1N=CN2[C@H]3[C@H](O)[C@H](OP(O)(O)=O)[C@@H](COP(O)(OP(O)(OCC(C)([C@H](C(NCCC(NCCSC(CC(C)(CC(O)=O)O)=O)=O)=O)O)C)=O)=O)O3

Molecular Formula

C27H44N7O20P3S

Molecular Weight

911.66

References & Citations

[1]Brian J Wong, et al. Evolution of function in the crotonase superfamily: (3S) -methylglutaconyl-CoA hydratase from Pseudomonas putida. Biochemistry. 2004 Apr 27;43 (16) :4646-54.|[2]Wong BJ, et al. Evolution of function in the crotonase superfamily: (3S) -methylglutaconyl-CoA hydratase from Pseudomonas putida. Biochemistry. 2004 Apr 27;43 (16) :4646-54.

Shipping Conditions

Room temperature

Scientific Category

Enzyme

Clinical Information

Phase 4

Frequently Asked Questions

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